May 9, 2019 · The translation of PDCD4 mRNA is inhibited by many kinds of miRNAs including miR21. The miR21 target site is located at nt233-349 of PDCD4 3′- ...
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Sep 30, 2011 · Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene 1995; 166: 297–301. Article CAS PubMed Google Scholar.
Jul 26, 2007 · Pdcd4 MA-3(C) was found to interact with the N-terminal domain of eIF4A through a conserved surface region encompassing the loop connecting ...
Pdcd4 MA-3 domains. We also show that contacts mediated by a conserved acidic patch on the middle MA-3 domain of Pdcd4 are essential for forming a tight ...
May 13, 2011 · The MA-3 domain competes with RNA for binding to eIF4A and is believed to stabilize the inactive conformation of eIF4A (22, 35). Pdcd4 has been ...
Feb 19, 2007 · Pdcd4 MA-3C was found to interact with the N-terminal domain of eIF4A through a conserved surface region encompassing the loop connecting α5 and ...
Nov 1, 2020 · L.C. Waters et al. Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: ...
Oct 6, 2020 · These findings indicate that the mTORC1/S6K/PDCD4/eIF4A axis has a pivotal role in the death versus slippage decision during mitotic arrest and ...
Abstract. Αn α-helical MA-3 domain appears in several translation initiation factors, including human eukaryotic translation initiation factor 4G (eIF4G) ...
Location of the interface between the Pdcd4 MA-3 M and MA-3 C domains. The histogram shown in panel a summarizes the combined differences between the ...